Thanks again, appreciate your assistance.
Before I look further into this I just tried the build with a USB 2.0 hub plugged into the USB 3.0 port and, hey presto, it worked.
More of a workaround that a solution but at least I can build them until I have looked further into it your advice.
These 2 in 1 HP X2 210 devices seem to be a bit of a pain in truth!